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A myAIHAteam Member asked a question 💭
Glasgow, UK
April 3
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A myAIHAteam Member

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April 3
myAIHAteam

Why has your hemoglobin gone down and reticulocytes gone up?

When you have autoimmune hemolytic anemia, your immune system attacks and destroys red blood cells faster than normal. This causes your hemoglobin levels to drop, leading to anemia.

Your body responds to this loss by trying to replace the destroyed red blood Show Full Answer

Why has your hemoglobin gone down and reticulocytes gone up?

When you have autoimmune hemolytic anemia, your immune system attacks and destroys red blood cells faster than normal. This causes your hemoglobin levels to drop, leading to anemia.

Your body responds to this loss by trying to replace the destroyed red blood cells as quickly as possible. It releases more reticulocytes (immature red blood cells) into your bloodstream to compensate for the ongoing destruction.

This pattern is actually typical of AIHA:
* Hemoglobin drops because red blood cells are being destroyed
* Reticulocytes increase as your body attempts to make up for the loss
* The higher reticulocyte count shows your bone marrow is working hard to produce new cells

A hemoglobin level below 8 grams per deciliter is considered more severe and may need closer monitoring. If your hemoglobin has dropped to 6 g/dL or lower, this requires immediate medical attention.

It's important to discuss these results with your doctor, as they may need to adjust your treatment plan to better control the hemolysis (red blood cell destruction).

April 3

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