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Real members of myAIHAteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
April 19
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myAIHAteam

Has anyone been treated with CAR T-cell therapy for secondary sickle cell hemolytic anemia?

CAR T-cell therapy is not mentioned as a treatment option for autoimmune hemolytic anemia (AIHA) in current medical literature. This therapy is primarily used for certain blood cancers, not for AIHA.

For secondary AIHA, the best Show Full Answer

Has anyone been treated with CAR T-cell therapy for secondary sickle cell hemolytic anemia?

CAR T-cell therapy is not mentioned as a treatment option for autoimmune hemolytic anemia (AIHA) in current medical literature. This therapy is primarily used for certain blood cancers, not for AIHA.

For secondary AIHA, the best approach is treating the underlying condition causing the anemia. Standard treatments for AIHA include:

* Corticosteroids (like prednisone) for warm AIHA
* Rituximab for both warm and cold AIHA
* Immunosuppressive drugs (azathioprine, mycophenolate mofetil, cyclophosphamide)
* Splenectomy in some cases
* Blood transfusions for severe anemia
* Plasma exchange for resistant cases

If you're interested in newer treatment approaches, clinical trials are exploring various medications for AIHA. It's worth discussing with your hematologist whether any clinical trials might be appropriate for your situation.

April 19